Errors of Fixed QT Heart Rate Corrections Used in the Assessment of Drug-Induced QTc Changes

The accuracy of studies of drug-induced QTc changes depends, among others, on the accuracy of heart rate correction of QT interval. It has been recognized that when a drug leads to substantial heart rate changes, fixed universal corrections cannot be used and that alternative methods such as subject...

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Detalles Bibliográficos
Autores principales: Hnatkova, Katerina, Vicente, Jose, Johannesen, Lars, Garnett, Christine, Stockbridge, Norman, Malik, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591442/
https://www.ncbi.nlm.nih.gov/pubmed/31275152
http://dx.doi.org/10.3389/fphys.2019.00635

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591442/
https://www.ncbi.nlm.nih.gov/pubmed/31275152
http://dx.doi.org/10.3389/fphys.2019.00635

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