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Errors of Fixed QT Heart Rate Corrections Used in the Assessment of Drug-Induced QTc Changes
The accuracy of studies of drug-induced QTc changes depends, among others, on the accuracy of heart rate correction of QT interval. It has been recognized that when a drug leads to substantial heart rate changes, fixed universal corrections cannot be used and that alternative methods such as subject...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591442/ https://www.ncbi.nlm.nih.gov/pubmed/31275152 http://dx.doi.org/10.3389/fphys.2019.00635 |