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Epigenetics in Sepsis: Understanding Its Role in Endothelial Dysfunction, Immunosuppression, and Potential Therapeutics

Sepsis has a complex pathophysiology in which both excessive and refractory inflammatory responses are hallmark features. Pro-inflammatory cytokine responses during the early stages are responsible for significant endothelial dysfunction, loss of endothelial integrity, and organ failure. In addition...

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Detalles Bibliográficos
Autores principales: Cross, Deborah, Drury, Ruth, Hill, Jennifer, Pollard, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591469/
https://www.ncbi.nlm.nih.gov/pubmed/31275313
http://dx.doi.org/10.3389/fimmu.2019.01363