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MicroRNA-146a improves sepsis-induced cardiomyopathy by regulating the TLR-4/NF-κB signaling pathway

The aim of the current study was to investigate the regulatory effect of miR-146a on the toll-like receptor 4 (TLR-4)/NF-κB pathway and therefore inflammation in septic cardiomyopathy. A total of 60 healthy male Sprague Dawley rats were equally divided into a control, LPS, miR-146a agonist and miR-1...

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Detalles Bibliográficos
Autores principales: Xie, Jin, Zhang, Lina, Fan, Xiaoyan, Dong, Xiaoqing, Zhang, Zhe, Fan, Wenxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591494/
https://www.ncbi.nlm.nih.gov/pubmed/31281454
http://dx.doi.org/10.3892/etm.2019.7657