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Enabling Large‐Scale Ex Vivo Production of Megakaryocytes from CD34(+) Cells Using Gas‐Permeable Surfaces

Patients suffering from acute or sustained thrombocytopenia require platelet transfusions, which are entirely donor‐based and limited by challenges related to storage and fluctuating supply. Developing cell‐culture technologies will enable ex vivo and donor‐independent platelet production. However,...

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Detalles Bibliográficos
Autores principales: Martinez, Andres F., Miller, William M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591548/
https://www.ncbi.nlm.nih.gov/pubmed/30848565
http://dx.doi.org/10.1002/sctm.18-0160