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Suppression of lncRNA RMRP ameliorates oxygen-glucose deprivation/re-oxygenation-induced neural cells injury by inhibiting autophagy and PI3K/Akt/mTOR-mediated apoptosis

The aberrant expression of lncRNAs has been inferred to be closely related with the progression of neural ischemia/reperfusion (I/R) injury. RMRP is an lncRNA associated with I/R injury. In order to determine the role of RMRP in I/R injury, the effects of RMRP knockdown on oxygen-glucose deprivation...

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Detalles Bibliográficos
Autores principales: Zhou, Zheyi, Xu, Hong, Liu, Baozhu, Dun, Linglu, Lu, Changjun, Cai, Yefeng, Wang, Honghao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591569/
https://www.ncbi.nlm.nih.gov/pubmed/30926681
http://dx.doi.org/10.1042/BSR20181367