A First-in-Human Study To Assess the Safety and Pharmacokinetics of LYS228, a Novel Intravenous Monobactam Antibiotic in Healthy Volunteers

Infections caused by antibiotic-resistant Gram-negative bacteria expressing extended-spectrum β-lactamases and carbapenemases are a growing global problem resulting in increased morbidity and mortality with limited treatment options. LYS228 is a novel intravenous monobactam antibiotic targeting peni...

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Detalles Bibliográficos
Autores principales: Osborn, Megan, Stachulski, Noah, Sun, Haiying, Blais, Johanne, Venishetty, Vinay, Raccuglia, Marc, Kankam, Martin, Colvin, Richard, Segal, Florencia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Clinical Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591616/
https://www.ncbi.nlm.nih.gov/pubmed/31061156
http://dx.doi.org/10.1128/AAC.02592-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591616/
https://www.ncbi.nlm.nih.gov/pubmed/31061156
http://dx.doi.org/10.1128/AAC.02592-18

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