Human Genomic Safe Harbors and the Suicide Gene‐Based Safeguard System for iPSC‐Based Cell Therapy

The use of human induced pluripotent stem cells (hiPSCs) and recent advances in cell engineering have opened new prospects for cell‐based therapy. However, there are concerns that must be addressed prior to their broad clinical applications and a major concern is tumorigenicity. Suicide gene approac...

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Detalles Bibliográficos
Autores principales: Kimura, Yasuyoshi, Shofuda, Tomoko, Higuchi, Yuichiro, Nagamori, Ippei, Oda, Masaaki, Nakamori, Masayuki, Onodera, Masafumi, Kanematsu, Daisuke, Yamamoto, Atsuyo, Katsuma, Asako, Suemizu, Hiroshi, Nakano, Toru, Kanemura, Yonehiro, Mochizuki, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Pluripotent Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591650/
https://www.ncbi.nlm.nih.gov/pubmed/30887735
http://dx.doi.org/10.1002/sctm.18-0039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591650/
https://www.ncbi.nlm.nih.gov/pubmed/30887735
http://dx.doi.org/10.1002/sctm.18-0039

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