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Opposite Expression Patterns of Spry3 and p75NTR in Cerebellar Vermis Suggest a Male-Specific Mechanism of Autism Pathogenesis

Autism is a genetically complex neurobehavioral disorder with a population prevalence of more than 1%. Cerebellar abnormalities, including Purkinje cell deficits in the vermis, are consistently reported, and rodent models of cerebellar dysfunction exhibit features analogous to human autism. We previ...

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Detalles Bibliográficos
Autores principales: Ning, Zhenfei, Williams, John M., Kumari, Romika, Baranov, Pavel V., Moore, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591651/
https://www.ncbi.nlm.nih.gov/pubmed/31275178
http://dx.doi.org/10.3389/fpsyt.2019.00416