Cargando…

Insights into Allosteric Control of Human Blood Group A and B Glycosyltransferases from Dynamic NMR

Human blood group A and B glycosyltransferases (GTA, GTB) are retaining glycosyltransferases, requiring a catalytic mechanism that conserves the anomeric configuration of the hexopyranose moiety of the donor substrate (UDP‐GalNAc, UDP‐Gal). Previous studies have shown that GTA and GTB cycle through...

Descripción completa

Detalles Bibliográficos
Autores principales: Flügge, Friedemann, Peters, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591795/
https://www.ncbi.nlm.nih.gov/pubmed/31289712
http://dx.doi.org/10.1002/open.201900116