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Master regulator analysis of paragangliomas carrying SDHx, VHL, or MAML3 genetic alterations
BACKGROUND: Succinate dehydrogenase (SDH) loss and mastermind-like 3 (MAML3) translocation are two clinically important genetic alterations that correlate with increased rates of metastasis in subtypes of human paraganglioma and pheochromocytoma (PPGL) neuroendocrine tumors. Although hypotheses prop...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591808/ https://www.ncbi.nlm.nih.gov/pubmed/31234811 http://dx.doi.org/10.1186/s12885-019-5813-z |