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Loss of skin elasticity is associated with pulmonary emphysema, biomarkers of inflammation, and matrix metalloproteinase activity in smokers

BACKGROUND: Elastin breakdown and the resultant loss of lung elastic recoil is a hallmark of pulmonary emphysema in susceptible individuals as a consequence of tobacco smoke exposure. Systemic alterations to the synthesis and degradation of elastin may be important to our understanding of disease ph...

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Detalles Bibliográficos
Autores principales: O’Brien, Michael E., Chandra, Divay, Wilson, Robert C., Karoleski, Chad M., Fuhrman, Carl R., Leader, Joseph K., Pu, Jiantao, Zhang, Yingze, Morris, Alison, Nouraie, Seyed, Bon, Jessica, Urban, Zsolt, Sciurba, Frank C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591816/
https://www.ncbi.nlm.nih.gov/pubmed/31234847
http://dx.doi.org/10.1186/s12931-019-1098-7