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Loss of skin elasticity is associated with pulmonary emphysema, biomarkers of inflammation, and matrix metalloproteinase activity in smokers
BACKGROUND: Elastin breakdown and the resultant loss of lung elastic recoil is a hallmark of pulmonary emphysema in susceptible individuals as a consequence of tobacco smoke exposure. Systemic alterations to the synthesis and degradation of elastin may be important to our understanding of disease ph...
Autores principales: | O’Brien, Michael E., Chandra, Divay, Wilson, Robert C., Karoleski, Chad M., Fuhrman, Carl R., Leader, Joseph K., Pu, Jiantao, Zhang, Yingze, Morris, Alison, Nouraie, Seyed, Bon, Jessica, Urban, Zsolt, Sciurba, Frank C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591816/ https://www.ncbi.nlm.nih.gov/pubmed/31234847 http://dx.doi.org/10.1186/s12931-019-1098-7 |
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