Inhibition of PI3K/Akt/mTOR signaling pathway alleviates ovarian cancer chemoresistance through reversing epithelial-mesenchymal transition and decreasing cancer stem cell marker expression

BACKGROUND: Ovarian cancer is the most common malignant tumor of the female reproductive tract. Chemoresistance is a major challenge for current ovarian cancer therapy. However, the mechanism underlying epithelial ovarian cancer (EOC) chemoresistance is not completely uncovered. The phosphatidylinos...

Descripción completa

Detalles Bibliográficos
Autores principales: Deng, Junli, Bai, Xupeng, Feng, Xiaojie, Ni, Jie, Beretov, Julia, Graham, Peter, Li, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591840/
https://www.ncbi.nlm.nih.gov/pubmed/31234823
http://dx.doi.org/10.1186/s12885-019-5824-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591840/
https://www.ncbi.nlm.nih.gov/pubmed/31234823
http://dx.doi.org/10.1186/s12885-019-5824-9

Ejemplares similares