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Long non-coding RNA HOXB-AS3 promotes myeloid cell proliferation and its higher expression is an adverse prognostic marker in patients with acute myeloid leukemia and myelodysplastic syndrome

BACKGROUND: Long non-coding RNAs (lncRNAs) represent the majority of cellular transcripts and play pivotal roles in hematopoiesis. However, their clinical relevance in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) remains largely unknown. Here, we investigated the functions of HOXB...

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Detalles Bibliográficos
Autores principales: Huang, Huai-Hsuan, Chen, Fei-Yun, Chou, Wen-Chien, Hou, Hsin-An, Ko, Bor-Sheng, Lin, Chien-Ting, Tang, Jih-Luh, Li, Chi-Cheng, Yao, Ming, Tsay, Woei, Hsu, Szu-Chun, Wu, Shang-Ju, Chen, Chien-Yuan, Huang, Shang-Yi, Tseng, Mei-Hsuan, Tien, Hwei-Fang, Chen, Ruey-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591843/
https://www.ncbi.nlm.nih.gov/pubmed/31234830
http://dx.doi.org/10.1186/s12885-019-5822-y