Dysregulated expression of hypoxia-inducible factors augments myofibroblasts differentiation in idiopathic pulmonary fibrosis

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is an age-related, progressive and lethal disease, whose pathogenesis is associated with fibroblasts/myofibroblasts foci that produce excessive extracellular matrix accumulation in lung parenchyma. Hypoxia has been described as a determinant factor in...

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Detalles Bibliográficos
Autores principales: Aquino-Gálvez, Arnoldo, González-Ávila, Georgina, Jiménez-Sánchez, Laura Lorena, Maldonado-Martínez, Héctor Aquiles, Cisneros, José, Toscano-Marquez, Fernanda, Castillejos-López, Manuel, Torres-Espíndola, Luz María, Velázquez-Cruz, Rafael, Rodríguez, Víctor Hugo Olivera, Flores-Soto, Edgar, Solís-Chagoyán, Héctor, Cabello, Carlos, Zúñiga, Joaquín, Romero, Yair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591870/
https://www.ncbi.nlm.nih.gov/pubmed/31234835
http://dx.doi.org/10.1186/s12931-019-1100-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591870/
https://www.ncbi.nlm.nih.gov/pubmed/31234835
http://dx.doi.org/10.1186/s12931-019-1100-4

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