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Performance of neural network basecalling tools for Oxford Nanopore sequencing

BACKGROUND: Basecalling, the computational process of translating raw electrical signal to nucleotide sequence, is of critical importance to the sequencing platforms produced by Oxford Nanopore Technologies (ONT). Here, we examine the performance of different basecalling tools, looking at accuracy a...

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Detalles Bibliográficos
Autores principales: Wick, Ryan R., Judd, Louise M., Holt, Kathryn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591954/
https://www.ncbi.nlm.nih.gov/pubmed/31234903
http://dx.doi.org/10.1186/s13059-019-1727-y