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Effect of overexpression of Oct4 and Sox2 genes on the biological and oncological characteristics of gastric cancer cells

Objective: Using the gastric cancer cell line SGC7901, we constructed a cell line that overexpressed octamer-binding protein 4 (Oct4) and SRY-box 2 (Sox2) to explore the stem cell oncological and biological characteristics of these cells and to elucidate the mechanisms of Oct4 and Sox2 in cancer. Me...

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Detalles Bibliográficos
Autores principales: Chen, Borong, Zhu, Zhipeng, Li, Lulu, Ye, Weipeng, Zeng, Junjie, Gao, Jin, Wang, Shengjie, Zhang, Liang, Huang, Zhengjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592062/
https://www.ncbi.nlm.nih.gov/pubmed/31417271
http://dx.doi.org/10.2147/OTT.S209734