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Exosomes from mesenchymal stem cells modulate endoplasmic reticulum stress to protect against nucleus pulposus cell death and ameliorate intervertebral disc degeneration in vivo

Objectives: Intervertebral disc degeneration (IDD) is widely accepted as a cause of low back pain and related degenerative musculoskeletal disorders. Nucleus pulposus (NP) cell apoptosis which is related to excessive endoplasmic reticulum (ER) stress in the intervertebral disc (IVD) could aggravate...

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Detalles Bibliográficos
Autores principales: Liao, Zhiwei, Luo, Rongjin, Li, Gaocai, Song, Yu, Zhan, Shengfeng, Zhao, Kangcheng, Hua, Wenbin, Zhang, Yukun, Wu, Xinghuo, Yang, Cao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592170/
https://www.ncbi.nlm.nih.gov/pubmed/31281533
http://dx.doi.org/10.7150/thno.33638