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Alarmin augments the antitumor immunity of lentiviral vaccine in ectopic, orthotopic and autochthonous hepatocellular carcinoma mice

It is a daunting therapeutic challenge to completely eradicate hepatocellular carcinoma (HCC) from patients. Alpha-fetoprotein (AFP) -based vaccines appear promising, however the efficacy needs to be improved. Methods: Here, we explore if fusing high-mobility group nucleosome binding protein 1 (HMGN...

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Detalles Bibliográficos
Autores principales: Liu, Zhili, Lu, Zhen, Jing, Renwei, Zuo, Bingfeng, Gao, Xianjun, Han, Gang, Qi, Han, Wu, Li, Liu, Yunde, Yin, Haifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592173/
https://www.ncbi.nlm.nih.gov/pubmed/31281528
http://dx.doi.org/10.7150/thno.32720