Blocking interleukin-6 trans-signaling protects against renal fibrosis by suppressing STAT3 activation

Rationale: Renal fibrosis is the terminal manifestation of chronic and irreversible renal disease. Effective therapies other than dialysis are extremely limited. In this study, we investigated the potential effects of targeting elevated interleukin-6 (IL-6) levels in the treatment of renal fibrosis....

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Detalles Bibliográficos
Autores principales: Chen, Wei, Yuan, Hui, Cao, Wenmin, Wang, Tianwei, Yu, Hang, Fu, Yao, Jiang, Bo, Zhou, Hong, Guo, Hongqian, Zhao, Xiaozhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592178/
https://www.ncbi.nlm.nih.gov/pubmed/31281526
http://dx.doi.org/10.7150/thno.32352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592178/
https://www.ncbi.nlm.nih.gov/pubmed/31281526
http://dx.doi.org/10.7150/thno.32352

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