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Blocking interleukin-6 trans-signaling protects against renal fibrosis by suppressing STAT3 activation
Rationale: Renal fibrosis is the terminal manifestation of chronic and irreversible renal disease. Effective therapies other than dialysis are extremely limited. In this study, we investigated the potential effects of targeting elevated interleukin-6 (IL-6) levels in the treatment of renal fibrosis....
Autores principales: | Chen, Wei, Yuan, Hui, Cao, Wenmin, Wang, Tianwei, Yu, Hang, Fu, Yao, Jiang, Bo, Zhou, Hong, Guo, Hongqian, Zhao, Xiaozhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592178/ https://www.ncbi.nlm.nih.gov/pubmed/31281526 http://dx.doi.org/10.7150/thno.32352 |
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