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Ascorbic acid induced HepG2 cells' apoptosis via intracellular reductive stress

Goals: Destruction of the redox balance in tumor cells is of great significance for triggering their apoptosis in clinical applications. We designed a pH sensitive multifunctional drug nanocarrier with controllable release of ascorbic acid under hypoxic environment to induce tumor cells' apopto...

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Detalles Bibliográficos
Autores principales: Gao, Xiaonan, Wei, Keyan, Hu, Bo, Xu, Kehua, Tang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592181/
https://www.ncbi.nlm.nih.gov/pubmed/31281544
http://dx.doi.org/10.7150/thno.33783