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Ascorbic acid induced HepG2 cells' apoptosis via intracellular reductive stress
Goals: Destruction of the redox balance in tumor cells is of great significance for triggering their apoptosis in clinical applications. We designed a pH sensitive multifunctional drug nanocarrier with controllable release of ascorbic acid under hypoxic environment to induce tumor cells' apopto...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Ivyspring International Publisher
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592181/ https://www.ncbi.nlm.nih.gov/pubmed/31281544 http://dx.doi.org/10.7150/thno.33783 |