Inhibition of neddylation induces mitotic defects and alters MKLP1 accumulation at the midbody during cytokinesis

The cullin-RING E3 ubiquitin ligases (CRLs) play crucial roles in modulating the stability of proteins in the cell and are, in turn, regulated by post-translational modification by the ubiquitin-like (Ubl) protein NEDD8. This process, termed neddylation, is reversible through the action of the COP9...

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Detalles Bibliográficos
Autores principales: Chung, Dudley, Salsman, Jayme, Dellaire, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592236/
https://www.ncbi.nlm.nih.gov/pubmed/31057046
http://dx.doi.org/10.1080/15384101.2019.1612696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592236/
https://www.ncbi.nlm.nih.gov/pubmed/31057046
http://dx.doi.org/10.1080/15384101.2019.1612696

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