Cargando…

Impact of eIF4E phosphorylation at Ser209 via MNK2a on tumour recurrence after curative surgery in localized clear cell renal cell carcinoma

Background: We investigated the roles of eIF4E phosphorylation (Ser209) in tumour recurrence after curative nephrectomy for localized clear cell renal cell carcinoma (ccRCC). Methods: Expression of eIF4E, p eIF4E and MNKs (MAPK interacting kinases), was evaluated in surgical specimens obtained from...

Descripción completa

Detalles Bibliográficos
Autores principales: Ichiyanagi, Osamu, Ito, Hiromi, Naito, Sei, Kabasawa, Takanobu, Kanno, Hidenori, Narisawa, Takafumi, Ushijima, Masaki, Kurota, Yuta, Ozawa, Michinobu, Sakurai, Toshihiko, Nishida, Hayato, Kato, Tomoyuki, Yamakawa, Mitsunori, Tsuchiya, Norihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592294/
https://www.ncbi.nlm.nih.gov/pubmed/31258849
http://dx.doi.org/10.18632/oncotarget.27017