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Targeting XIST induced apoptosis of human osteosarcoma cells by activation of NF-kB/PUMA signal
The long noncoding RNA X-inactive specific transcript (XIST) plays vital roles in tumor progression. However, the underlying mechanisms remain unclear. This study investigated the effects and mechanisms of targeting XIST on osteosarcoma (OS) cells in vitro and in vivo. We used shRNA to knockdown XIS...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592364/ https://www.ncbi.nlm.nih.gov/pubmed/31189404 http://dx.doi.org/10.1080/21655979.2019.1631104 |