Cargando…

Targeting XIST induced apoptosis of human osteosarcoma cells by activation of NF-kB/PUMA signal

The long noncoding RNA X-inactive specific transcript (XIST) plays vital roles in tumor progression. However, the underlying mechanisms remain unclear. This study investigated the effects and mechanisms of targeting XIST on osteosarcoma (OS) cells in vitro and in vivo. We used shRNA to knockdown XIS...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Weiliang, Gao, Jisheng, Chen, Longying, Ren, Yande, Ma, Jinfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592364/
https://www.ncbi.nlm.nih.gov/pubmed/31189404
http://dx.doi.org/10.1080/21655979.2019.1631104