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A telomerase with novel non-canonical roles: TERT controls cellular aggregation and tissue size in Dictyostelium

Telomerase, particularly its main subunit, the reverse transcriptase, TERT, prevents DNA erosion during eukaryotic chromosomal replication, but also has poorly understood non-canonical functions. Here, in the model social amoeba Dictyostelium discoideum, we show that the protein encoded by tert has...

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Detalles Bibliográficos
Autores principales: Nassir, Nasna, Hyde, Geoffrey J., Baskar, Ramamurthy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592521/
https://www.ncbi.nlm.nih.gov/pubmed/31237867
http://dx.doi.org/10.1371/journal.pgen.1008188