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A telomerase with novel non-canonical roles: TERT controls cellular aggregation and tissue size in Dictyostelium
Telomerase, particularly its main subunit, the reverse transcriptase, TERT, prevents DNA erosion during eukaryotic chromosomal replication, but also has poorly understood non-canonical functions. Here, in the model social amoeba Dictyostelium discoideum, we show that the protein encoded by tert has...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592521/ https://www.ncbi.nlm.nih.gov/pubmed/31237867 http://dx.doi.org/10.1371/journal.pgen.1008188 |