Cargando…
A telomerase with novel non-canonical roles: TERT controls cellular aggregation and tissue size in Dictyostelium
Telomerase, particularly its main subunit, the reverse transcriptase, TERT, prevents DNA erosion during eukaryotic chromosomal replication, but also has poorly understood non-canonical functions. Here, in the model social amoeba Dictyostelium discoideum, we show that the protein encoded by tert has...
Autores principales: | Nassir, Nasna, Hyde, Geoffrey J., Baskar, Ramamurthy |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592521/ https://www.ncbi.nlm.nih.gov/pubmed/31237867 http://dx.doi.org/10.1371/journal.pgen.1008188 |
Ejemplares similares
-
Regulation of aggregate size and pattern by adenosine and caffeine in cellular slime molds
por: Jaiswal, Pundrik, et al.
Publicado: (2012) -
TERT Promoter Mutations and Telomerase in Melanoma
por: Guo, Yuchen, et al.
Publicado: (2022) -
Dictyostelium AMPKα regulates aggregate size and cell-type patterning
por: Maurya, Ranjana, et al.
Publicado: (2017) -
Non-canonical Roles of Telomerase: Unraveling the Imbroglio
por: Ségal-Bendirdjian, Evelyne, et al.
Publicado: (2019) -
Tianshengyuan-1 (TSY-1) regulates cellular Telomerase activity by methylation of TERT promoter
por: Yu, Weibo, et al.
Publicado: (2016)