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Anopheles gambiae TEP1 forms a complex with the coiled-coil domain of LRIM1/APL1C following a conformational change in the thioester domain

The complement-like protein thioester-containing protein 1 (TEP1) is a key factor in the immune response of the malaria vector Anopheles gambiae to pathogens. Multiple allelic variants of TEP1 have been identified in laboratory strains and in the field, and are correlated with distinct immunophenoty...

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Detalles Bibliográficos
Autores principales: Williams, Marni, Contet, Alicia, Hou, Chun-Feng David, Levashina, Elena A., Baxter, Richard H. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592522/
https://www.ncbi.nlm.nih.gov/pubmed/31237887
http://dx.doi.org/10.1371/journal.pone.0218203