Detecting T cell receptors involved in immune responses from single repertoire snapshots

Hypervariable T cell receptors (TCRs) play a key role in adaptive immunity, recognizing a vast diversity of pathogen-derived antigens. Our ability to extract clinically relevant information from large high-throughput sequencing of TCR repertoires (RepSeq) data is limited, because little is known abo...

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Detalles Bibliográficos
Autores principales: Pogorelyy, Mikhail V., Minervina, Anastasia A., Shugay, Mikhail, Chudakov, Dmitriy M., Lebedev, Yuri B., Mora, Thierry, Walczak, Aleksandra M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592544/
https://www.ncbi.nlm.nih.gov/pubmed/31194732
http://dx.doi.org/10.1371/journal.pbio.3000314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592544/
https://www.ncbi.nlm.nih.gov/pubmed/31194732
http://dx.doi.org/10.1371/journal.pbio.3000314

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