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Detecting T cell receptors involved in immune responses from single repertoire snapshots

Hypervariable T cell receptors (TCRs) play a key role in adaptive immunity, recognizing a vast diversity of pathogen-derived antigens. Our ability to extract clinically relevant information from large high-throughput sequencing of TCR repertoires (RepSeq) data is limited, because little is known abo...

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Detalles Bibliográficos
Autores principales:	Pogorelyy, Mikhail V., Minervina, Anastasia A., Shugay, Mikhail, Chudakov, Dmitriy M., Lebedev, Yuri B., Mora, Thierry, Walczak, Aleksandra M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592544/ https://www.ncbi.nlm.nih.gov/pubmed/31194732 http://dx.doi.org/10.1371/journal.pbio.3000314

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