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Integrative modeling of the HIV-1 ribonucleoprotein complex

A coarse-grain computational method integrates biophysical and structural data to generate models of HIV-1 genomic RNA, nucleocapsid and integrase condensed into a mature ribonucleoprotein complex. Several hypotheses for the initial structure of the genomic RNA and oligomeric state of integrase are...

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Detalles Bibliográficos
Autores principales: Goodsell, David S., Jewett, Andrew, Olson, Arthur J., Forli, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592547/
https://www.ncbi.nlm.nih.gov/pubmed/31194731
http://dx.doi.org/10.1371/journal.pcbi.1007150