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Abelmoschus esculentus subfractions attenuate beta amyloid-induced neuron apoptosis by regulating DPP-4 with improving insulin resistance signals

The association of Alzheimer disease (AD) and Diabetes (DM) is less clear. Accumulation of beta amyloid (Aβ) and presence of hyperphosphorylated tau (p-tau) are hallmarks of AD, spreading in the region where insulin receptors are also found. Aβ exerts neuron toxicity, and could disturb insulin signa...

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Detalles Bibliográficos
Autores principales: Huang, Chien-Ning, Wang, Chau-Jong, Lin, Chih-Li, Yen, An-Ting, Li, Hsin-Hua, Peng, Chiung-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592593/
https://www.ncbi.nlm.nih.gov/pubmed/31237881
http://dx.doi.org/10.1371/journal.pone.0217400