Haplotypes spanning centromeric regions reveal persistence of large blocks of archaic DNA

Despite critical roles in chromosome segregation and disease, the repetitive structure and vast size of centromeres and their surrounding heterochromatic regions impede studies of genomic variation. Here we report the identification of large-scale haplotypes (cenhaps) in humans that span the centrom...

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Detalles Bibliográficos
Autores principales: Langley, Sasha A, Miga, Karen H, Karpen, Gary H, Langley, Charles H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Evolutionary Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592686/
https://www.ncbi.nlm.nih.gov/pubmed/31237235
http://dx.doi.org/10.7554/eLife.42989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592686/
https://www.ncbi.nlm.nih.gov/pubmed/31237235
http://dx.doi.org/10.7554/eLife.42989

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