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CG-dinucleotide suppression enables antiviral defense targeting non-self RNA
Vertebrate genomes exhibit marked CG-suppression, that is lower than expected numbers of 5′-CG-3′ dinucleotides(1). This feature is likely due to C-to-T mutations that have accumulated over hundreds of millions of years, driven by CG-specific DNA methyl transferases and spontaneous methyl-cytosine d...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592701/ https://www.ncbi.nlm.nih.gov/pubmed/28953888 http://dx.doi.org/10.1038/nature24039 |