EGF receptor (EGFR) inhibition promotes a slow-twitch oxidative, over a fast-twitch, muscle phenotype

A low quadriceps slow-twitch (ST), oxidative (relative to fast-twitch) fiber proportion is prevalent in chronic diseases such Chronic Obstructive Pulmonary Disease (COPD) and is associated with exercise limitation and poor outcomes. Benefits of an increased ST fiber proportion are demonstrated in ge...

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Detalles Bibliográficos
Autores principales: Ciano, Margherita, Mantellato, Giada, Connolly, Martin, Paul-Clark, Mark, Willis-Owen, Saffron, Moffatt, Miriam F., Cookson, William O. C. M., Mitchell, Jane A., Polkey, Michael I., Hughes, Simon M., Kemp, Paul R., Natanek, S. Amanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592914/
https://www.ncbi.nlm.nih.gov/pubmed/31239465
http://dx.doi.org/10.1038/s41598-019-45567-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592914/
https://www.ncbi.nlm.nih.gov/pubmed/31239465
http://dx.doi.org/10.1038/s41598-019-45567-4

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