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Finding Friends in the Crowd: Three-Dimensional Cliques of Topological Genomic Domains
The mammalian genome is intricately folded in a three-dimensional topology believed to be important for the orchestration of gene expression regulating development, differentiation and tissue homeostasis. Important features of spatial genome conformation in the nucleus are promoter-enhancer contacts...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593077/ https://www.ncbi.nlm.nih.gov/pubmed/31275364 http://dx.doi.org/10.3389/fgene.2019.00602 |