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Finding Friends in the Crowd: Three-Dimensional Cliques of Topological Genomic Domains

The mammalian genome is intricately folded in a three-dimensional topology believed to be important for the orchestration of gene expression regulating development, differentiation and tissue homeostasis. Important features of spatial genome conformation in the nucleus are promoter-enhancer contacts...

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Detalles Bibliográficos
Autores principales: Collas, Philippe, Liyakat Ali, Tharvesh M., Brunet, Annaël, Germier, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593077/
https://www.ncbi.nlm.nih.gov/pubmed/31275364
http://dx.doi.org/10.3389/fgene.2019.00602