Iron Deposition Leads to Hyperphosphorylation of Tau and Disruption of Insulin Signaling

Iron deposition in the brain is an early issue in Alzheimer's disease (AD). However, the pathogenesis of iron-induced pathological changes in AD remains elusive. Insulin resistance in brains is an essential feature of AD. Previous studies determined that insulin resistance is involved in the de...

Descripción completa

Detalles Bibliográficos
Autores principales: Wan, Wenbin, Cao, Lan, Kalionis, Bill, Murthi, Padma, Xia, Shijin, Guan, Yangtai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593079/
https://www.ncbi.nlm.nih.gov/pubmed/31275224
http://dx.doi.org/10.3389/fneur.2019.00607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593079/
https://www.ncbi.nlm.nih.gov/pubmed/31275224
http://dx.doi.org/10.3389/fneur.2019.00607

Ejemplares similares