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Iron Deposition Leads to Hyperphosphorylation of Tau and Disruption of Insulin Signaling

Iron deposition in the brain is an early issue in Alzheimer's disease (AD). However, the pathogenesis of iron-induced pathological changes in AD remains elusive. Insulin resistance in brains is an essential feature of AD. Previous studies determined that insulin resistance is involved in the de...

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Detalles Bibliográficos
Autores principales:	Wan, Wenbin, Cao, Lan, Kalionis, Bill, Murthi, Padma, Xia, Shijin, Guan, Yangtai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593079/ https://www.ncbi.nlm.nih.gov/pubmed/31275224 http://dx.doi.org/10.3389/fneur.2019.00607

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