The Bone Morphogenetic Protein Signaling Inhibitor LDN-193189 Enhances Metastasis Development in Mice

Breast cancer with bone metastasis is essentially incurable with current anticancer therapies. The bone morphogenetic protein (BMP) pathway is an attractive therapeutic candidate, as it is involved in the bone turnover and in cancer cell formation and their colonization of distant organs such as the...

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Detalles Bibliográficos
Autores principales: Vollaire, Julien, Machuca-Gayet, Irma, Lavaud, Jonathan, Bellanger, Aurélie, Bouazza, Lamia, El Moghrabi, Soumaya, Treilleux, Isabelle, Coll, Jean-Luc, Peyruchaud, Olivier, Josserand, Véronique, Cohen, Pascale A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593094/
https://www.ncbi.nlm.nih.gov/pubmed/31275146
http://dx.doi.org/10.3389/fphar.2019.00667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593094/
https://www.ncbi.nlm.nih.gov/pubmed/31275146
http://dx.doi.org/10.3389/fphar.2019.00667

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