Immune Reaction to Type XVII Collagen Induces Intramolecular and Intermolecular Epitope Spreading in Experimental Bullous Pemphigoid Models

Bullous pemphigoid (BP), the most common autoimmune blistering disease, is induced by autoantibodies to type XVII collagen (COL17). Previous studies demonstrated that COL17 harbors several epitopes targeted by autoreactive T and B cells and that the target epitopes change sequentially during the dis...

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Detalles Bibliográficos
Autores principales: Ujiie, Hideyuki, Yoshimoto, Norihiro, Natsuga, Ken, Muramatsu, Ken, Iwata, Hiroaki, Nishie, Wataru, Shimizu, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593113/
https://www.ncbi.nlm.nih.gov/pubmed/31275329
http://dx.doi.org/10.3389/fimmu.2019.01410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593113/
https://www.ncbi.nlm.nih.gov/pubmed/31275329
http://dx.doi.org/10.3389/fimmu.2019.01410

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