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Understanding the Dynamics of T-Cell Activation in Health and Disease Through the Lens of Computational Modeling
T cells in the immune system are activated by binding to foreign peptides (from an external pathogen) or mutant peptide (derived from endogenous proteins) displayed on the surface of a diseased cell. This triggers a series of intracellular signaling pathways, which ultimately dictate the response of...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Clinical Oncology
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593125/ https://www.ncbi.nlm.nih.gov/pubmed/30689404 http://dx.doi.org/10.1200/CCI.18.00057 |