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Active Tonic mTORC1 Signals Shape Baseline Translation in Naive T Cells
Naive CD4(+) T cells are an example of dynamic cell homeostasis: T cells need to avoid autoreactivity while constantly seeing self-peptides, yet they must be primed to react to foreign antigens during infection. The instructive signals that balance this primed yet quiescent state are unknown. Intera...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593126/ https://www.ncbi.nlm.nih.gov/pubmed/31067469 http://dx.doi.org/10.1016/j.celrep.2019.04.037 |