Cargando…

Lipid Metabolic Pathways Confer the Immunosuppressive Function of Myeloid-Derived Suppressor Cells in Tumor

Myeloid-derived suppressor cells (MDSCs) play crucial roles in tumorigenesis and their inhibition is critical for successful cancer immunotherapy. MDSCs undergo metabolic reprogramming from glycolysis to fatty acid oxidation (FAO) and oxidative phosphorylation led by lipid accumulation in tumor. Inc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yan, Dehong, Adeshakin, Adeleye O., Xu, Meichen, Afolabi, Lukman O., Zhang, Guizhong, Chen, Youhai H., Wan, Xiaochun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593140/ https://www.ncbi.nlm.nih.gov/pubmed/31275326 http://dx.doi.org/10.3389/fimmu.2019.01399

Ejemplares similares

Regulating Histone Deacetylase Signaling Pathways of Myeloid-Derived Suppressor Cells Enhanced T Cell-Based Immunotherapy
por: Adeshakin, Adeleye O., et al.
Publicado: (2022)

Mechanisms for Modulating Anoikis Resistance in Cancer and the Relevance of Metabolic Reprogramming
por: Adeshakin, Funmilayo O., et al.
Publicado: (2021)

Lipidomics data showing the effect of lipofermata on myeloid-derived suppressor cells in the spleens of tumor-bearing mice
por: Adeshakin, Adeleye Oluwatosin, et al.
Publicado: (2021)

Synergistic Tumor Cytolysis by NK Cells in Combination With a Pan-HDAC Inhibitor, Panobinostat
por: Afolabi, Lukman O., et al.
Publicado: (2021)

Targeting Oxidative Phosphorylation-Proteasome Activity in Extracellular Detached Cells Promotes Anoikis and Inhibits Metastasis
por: Adeshakin, Funmilayo O., et al.
Publicado: (2021)

Upregulation of V-ATPase by STAT3 Activation Promotes Anoikis Resistance and Tumor Metastasis
por: Adeshakin, Funmilayo O., et al.
Publicado: (2021)

Targeting Myeloid-Derived Suppressor Cells to Bypass Tumor-Induced Immunosuppression
por: Fleming, Viktor, et al.
Publicado: (2018)

Myeloid Derived Suppressor Cells: Key Drivers of Immunosuppression in Ovarian Cancer
por: Baert, Thaïs, et al.
Publicado: (2019)

Myeloid-Derived Suppressor Cell Differentiation in Cancer: Transcriptional Regulators and Enhanceosome-Mediated Mechanisms
por: Fultang, Norman, et al.
Publicado: (2021)

TIPE2 specifies the functional polarization of myeloid-derived suppressor cells during tumorigenesis
por: Yan, Dehong, et al.
Publicado: (2019)

Myeloid-Derived Suppressor Cells Are Increased in Lung Transplant Recipients and Regulated by Immunosuppressive Therapy
por: Iglesias-Escudero, María, et al.
Publicado: (2022)

TRAF6 Regulates the Immunosuppressive Effects of Myeloid-Derived Suppressor Cells in Tumor-Bearing Host
por: Song, Ge, et al.
Publicado: (2021)

Interleukin-6 Trans-Signaling Pathway Promotes Immunosuppressive Myeloid-Derived Suppressor Cells via Suppression of Suppressor of Cytokine Signaling 3 in Breast Cancer
por: Jiang, Mengmeng, et al.
Publicado: (2017)

Myeloid-Derived Suppressor Cells in Sepsis
por: Schrijver, Irene T., et al.
Publicado: (2019)

Clinical Relevance and Immunosuppressive Pattern of Circulating and Infiltrating Subsets of Myeloid-Derived Suppressor Cells (MDSCs) in Epithelial Ovarian Cancer
por: Okła, Karolina, et al.
Publicado: (2019)

LncRNAs has been identified as regulators of Myeloid-derived suppressor cells in lung cancer
por: Liu, Yifan, et al.
Publicado: (2023)

The Yin and Yang of Myeloid Derived Suppressor Cells
por: Budhwar, Snehil, et al.
Publicado: (2018)

Myeloid-Derived Suppressor Cells in Lung Transplantation
por: Heigl, Tobias, et al.
Publicado: (2019)

Myeloid-Derived Suppressor Cells in Colorectal Cancer
por: Sieminska, Izabela, et al.
Publicado: (2020)

Myeloid-derived suppressor cells and pulmonary hypertension
por: Zhang, Hui, et al.
Publicado: (2023)

Intracellular Lipid Accumulation Drives the Differentiation of Decidual Polymorphonuclear Myeloid-Derived Suppressor Cells via Arachidonic Acid Metabolism
por: Wang, Qiaohong, et al.
Publicado: (2022)

TGF-β Enhances Immunosuppression of Myeloid-Derived Suppressor Cells to Induce Transplant Immune Tolerance Through Affecting Arg-1 Expression
por: Cao, Peng, et al.
Publicado: (2022)

CD317 maintains proteostasis and cell survival in response to proteasome inhibitors by targeting calnexin for RACK1-mediated autophagic degradation
por: Cheng, Jian, et al.
Publicado: (2023)

The Role of Myeloid-Derived Suppressor Cells in Immune Ontogeny
por: Gantt, Soren, et al.
Publicado: (2014)

Monocytic Myeloid-Derived Suppressor Cells in Chronic Infections
por: Dorhoi, Anca, et al.
Publicado: (2018)

Myeloid-Derived Suppressor Cells: Ductile Targets in Disease
por: Consonni, Francesca Maria, et al.
Publicado: (2019)

The Emerging Role of Myeloid-Derived Suppressor Cells in Tuberculosis
por: Magcwebeba, Tandeka, et al.
Publicado: (2019)

Myeloid-Derived Suppressor Cells: Not Only in Tumor Immunity
por: Pawelec, Graham, et al.
Publicado: (2019)

Myeloid-Derived Suppressor Cells in Pregnancy and the Neonatal Period
por: Köstlin-Gille, Natascha, et al.
Publicado: (2020)

Editorial: Myeloid Derived Suppressor Cells as Disease Modulators
por: Finn, Olivera J., et al.
Publicado: (2020)

Granulocytic Myeloid-Derived Suppressor Cells in Cystic Fibrosis
por: Tucker, Samantha L., et al.
Publicado: (2021)

The role of myeloid derived suppressor cells in musculoskeletal disorders
por: Ren, Yi, et al.
Publicado: (2023)

Myeloid-Derived Suppressor Cells in Patients With Acute Pancreatitis With Increased Inhibitory Function
por: Ding, Lili, et al.
Publicado: (2022)

Long Non-Coding RNA HOXA Transcript Antisense RNA Myeloid-Specific 1–HOXA1 Axis Downregulates the Immunosuppressive Activity of Myeloid-Derived Suppressor Cells in Lung Cancer
por: Tian, Xinyu, et al.
Publicado: (2018)

Immunosuppressive Effects of Myeloid-Derived Suppressor Cells in Cancer and Immunotherapy
por: Krishnamoorthy, Mithunah, et al.
Publicado: (2021)

Pam2 lipopeptides enhance the immunosuppressive activity of monocytic myeloid-derived suppressor cells by STAT3 signal in chronic inflammation
por: Zhan, Xiaoxia, et al.
Publicado: (2022)

A Complex Metabolic Network Confers Immunosuppressive Functions to Myeloid-Derived Suppressor Cells (MDSCs) within the Tumour Microenvironment
por: Hofer, Francesca, et al.
Publicado: (2021)

Roles of Myeloid-Derived Suppressor Cell Subpopulations in Autoimmune Arthritis
por: Li, Min, et al.
Publicado: (2018)

Corrigendum: The Emerging Role of Myeloid-Derived Suppressor Cells in Tuberculosis
por: Magcwebeba, Tandeka, et al.
Publicado: (2019)

Expansion of Polymorphonuclear Myeloid-Derived Suppressor Cells in Patients With Gout
por: Zhong, Limei, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_b1b80lmfdbp8m3hj97vq5quh3c