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Protective Effect of Melatonin Against Polymicrobial Sepsis Is Mediated by the Anti-bacterial Effect of Neutrophils

Sepsis is an infection- or toxin-mediated systemic inflammatory syndrome. Previous studies have shown that melatonin, the primary hormone produced by the pineal gland, attenuates the effect of polymicrobial infection-mediated septic shock in animals. However, the mechanism of the anti-septic effect...

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Detalles Bibliográficos
Autores principales: Xu, Li, Zhang, Wei, Kwak, Minseok, Zhang, LiJun, Lee, Peter C. W., Jin, Jun-O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593141/
https://www.ncbi.nlm.nih.gov/pubmed/31275316
http://dx.doi.org/10.3389/fimmu.2019.01371