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The Functional Mammalian CRES (Cystatin-Related Epididymal Spermatogenic) Amyloid is Antiparallel β-Sheet Rich and Forms a Metastable Oligomer During Assembly

An amyloid matrix composed of several family 2 cystatins, including the reproductive cystatin CRES, is an integral structure in the mouse epididymal lumen and has proposed functions in sperm maturation and protection. Understanding how CRES amyloid assembles in vitro may provide clues on how the epi...

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Detalles Bibliográficos
Autores principales: Do, Hoa Quynh, Hewetson, Aveline, Myers, Caitlyn, Khan, Nazmul H., Hastert, Mary Catherine, M. Harsini, Faraz, Latham, Michael P., Wylie, Benjamin J., Sutton, R. Bryan, Cornwall, Gail A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593142/
https://www.ncbi.nlm.nih.gov/pubmed/31239483
http://dx.doi.org/10.1038/s41598-019-45545-w