Cargando…
The Functional Mammalian CRES (Cystatin-Related Epididymal Spermatogenic) Amyloid is Antiparallel β-Sheet Rich and Forms a Metastable Oligomer During Assembly
An amyloid matrix composed of several family 2 cystatins, including the reproductive cystatin CRES, is an integral structure in the mouse epididymal lumen and has proposed functions in sperm maturation and protection. Understanding how CRES amyloid assembles in vitro may provide clues on how the epi...
Autores principales: | Do, Hoa Quynh, Hewetson, Aveline, Myers, Caitlyn, Khan, Nazmul H., Hastert, Mary Catherine, M. Harsini, Faraz, Latham, Michael P., Wylie, Benjamin J., Sutton, R. Bryan, Cornwall, Gail A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593142/ https://www.ncbi.nlm.nih.gov/pubmed/31239483 http://dx.doi.org/10.1038/s41598-019-45545-w |
Ejemplares similares
-
Cross-seeding between the functional amyloidogenic CRES and CRES3 family members and their regulation of Aβ assembly
por: Do, Hoa Quynh, et al.
Publicado: (2021) -
Host defense functions of the epididymal amyloid matrix
por: Myers, Caitlyn, et al.
Publicado: (2022) -
Functional Amyloids in Reproduction
por: Hewetson, Aveline, et al.
Publicado: (2017) -
Nonpathological Extracellular Amyloid Is Present during Normal Epididymal Sperm Maturation
por: Whelly, Sandra, et al.
Publicado: (2012) -
Antimicrobial Activity and Molecular Mechanism of the CRES Protein
por: Wang, Li, et al.
Publicado: (2012)