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Photoredox-Catalyzed Enantioselective α-Deuteration of Azaarenes with D(2)O
The site-specific incorporation of deuterium (D) into small molecules is frequently used to access isotopically labeled compounds with broad utility in many research areas, such as drug development, mechanistic studies, and NMR analyses. Nevertheless, the deuteration of a stereocenter in an enantios...
Autores principales: | Shao, Tianju, Li, Yajuan, Ma, Nana, Li, Chunyang, Chai, Guobi, Zhao, Xiaowei, Qiao, Baokun, Jiang, Zhiyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593145/ https://www.ncbi.nlm.nih.gov/pubmed/31229890 http://dx.doi.org/10.1016/j.isci.2019.06.007 |
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