Potential Use of Gluconate in Cancer Therapy

We have recently discovered that cancer cells take up extracellular citrate through plasma membrane citrate transporter (pmCiC) and advantageously use citrate for their metabolism. Citrate uptake can be blocked with gluconate and this results in decreased tumor growth and altered metabolic character...

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Detalles Bibliográficos
Autores principales: Mycielska, Maria E., Mohr, Markus T. J., Schmidt, Katharina, Drexler, Konstantin, Rümmele, Petra, Haferkamp, Sebastian, Schlitt, Hans J., Gaumann, Andreas, Adamski, Jerzy, Geissler, Edward K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593216/
https://www.ncbi.nlm.nih.gov/pubmed/31275855
http://dx.doi.org/10.3389/fonc.2019.00522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593216/
https://www.ncbi.nlm.nih.gov/pubmed/31275855
http://dx.doi.org/10.3389/fonc.2019.00522

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